Human NDST3 activation kit by CRISPRa

SKU GA106231

NDST3 CRISPRa kit - CRISPR gene activation of human N-deacetylase and N-sulfotransferase 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NDST3
• Locus ID: 9348
• Components:

  GA106231G1, NDST3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106231G2, NDST3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106231G3, NDST3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004784, NR_146513, NR_146514
• UniProt ID: O95803
• Synonyms: HSST3
• Summary: This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq, Nov 2008]