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Human DCAMKL1 (DCLK1) activation kit by CRISPRa

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SKU
GA106133
DCLK1 CRISPRa kit - CRISPR gene activation of human doublecortin like kinase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA806542 DCLK1 mouse monoclonal antibody,clone OTI1F8 100 ul
$447.00
RC217050 DCLK1 (Myc-DDK-tagged)-Human doublecortin-like kinase 1 (DCLK1), transcript variant 1
10 ug
$1,001.00

Other products for "DCLK1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DCLK1
Locus ID 9201
Components

GA106133G1, DCAMKL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106133G2, DCAMKL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106133G3, DCAMKL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001195415, NM_001195416, NM_001195430, NM_004734, NM_001330071, NM_001330072
UniProt ID O15075
Synonyms CL1; CLICK1; DCAMKL1; DCDC3A; DCLK
Summary This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.provided by RefSeq, Sep 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN217050 DCLK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217050BN DCLK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217050LP DCLK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217050RB DCLK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN417050 DCLK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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