Human JMJD7-PLA2G4B activation kit by CRISPRa

SKU GA105758

JMJD7-PLA2G4B CRISPRa kit - CRISPR gene activation of human JMJD7-PLA2G4B readthrough

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: JMJD7-PLA2G4B
• Locus ID: 8681
• Components:

  GA105758G1, JMJD7-PLA2G4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105758G2, JMJD7-PLA2G4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105758G3, JMJD7-PLA2G4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001198588, NM_005090, NR_015346
• UniProt ID: P0C869
• Synonyms: cPLA2-beta; HsT16992
• Summary: This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Oct 2013]