Human Syntaxin 16 (STX16) activation kit by CRISPRa

SKU GA105754

STX16 CRISPRa kit - CRISPR gene activation of human syntaxin 16

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: STX16
• Locus ID: 8675
• Components:

  GA105754G1, Syntaxin 16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105754G2, Syntaxin 16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105754G3, Syntaxin 16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001001433, NM_001001434, NM_001134772, NM_001134773, NM_001204868, NM_003763, NR_037941, NR_037942, NR_037943
• UniProt ID: O14662
• Synonyms: SYN16
• Summary: This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011]