Human RTCD1 (RTCA) activation kit by CRISPRa

SKU GA105718

RTCA CRISPRa kit - CRISPR gene activation of human RNA 3'-terminal phosphate cyclase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RTCA
• Locus ID: 8634
• Components:

  GA105718G1, RTCD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105718G2, RTCD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105718G3, RTCD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001130841, NM_003729
• UniProt ID: O00442
• Synonyms: RPC; RTC1; RTCD1
• Summary: This gene encodes a member of the RNA 3'-phosphate cyclase family. The encoded protein plays a role in RNA metabolism by catalyzing the ATP-dependent conversion of the 3'-phosphate of RNA substrates to a 2',3'-cyclic phosphodiester. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]