Human CGGBP1 activation kit by CRISPRa

SKU
GA105659
CGGBP1 CRISPRa kit - CRISPR gene activation of human CGG triplet repeat binding protein 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CGGBP1
Locus ID 8545
Components

GA105659G1, CGGBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105659G2, CGGBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105659G3, CGGBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001008390, NM_001195308, NM_003663
UniProt ID Q9UFW8
Synonyms CGGBP; p20-CGGBP
Summary This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences. provided by RefSeq, Jul 2017
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Other Versions
SKU Description Size Price
KN408653 CGGBP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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