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Human IFITM1 activation kit by CRISPRa

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SKU
GA105635
IFITM1 CRISPRa kit - CRISPR gene activation of human interferon induced transmembrane protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC201617 IFITM1 (Myc-DDK-tagged)-Human interferon induced transmembrane protein 1 (9-27) (IFITM1)
10 ug
$150.00

Other products for "IFITM1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IFITM1
Locus ID 8519
Components

GA105635G1, IFITM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105635G2, IFITM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105635G3, IFITM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_003641
UniProt ID P13164
Synonyms 9-27; CD225; DSPA2a; IFI17; LEU13
Summary IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN201617 IFITM1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201617BN IFITM1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201617LP IFITM1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201617RB IFITM1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401617 IFITM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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