Human Gemin 2 (GEMIN2) activation kit by CRISPRa

SKU
GA105608
GEMIN2 CRISPRa kit - CRISPR gene activation of human gem nuclear organelle associated protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GEMIN2
Locus ID 8487
Components

GA105608G1, Gemin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105608G2, Gemin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105608G3, Gemin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001009182, NM_001009183, NM_003616
UniProt ID O14893
Synonyms SIP1; SIP1-delta
Summary This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. provided by RefSeq, Aug 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN411219 GEMIN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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