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Human GDF 5 (GDF5) activation kit by CRISPRa

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SKU
GA105437
GDF5 CRISPRa kit - CRISPR gene activation of human growth differentiation factor 5
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC207105 GDF5 (Myc-DDK-tagged)-Human growth differentiation factor 5 (GDF5)
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GDF5
Locus ID 8200
Components

GA105437G1, GDF 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105437G2, GDF 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105437G3, GDF 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000557, NM_001319138
UniProt ID P43026
Synonyms BDA1C; BMP-14; BMP14; CDMP1; LAP-4; LAP4; OS5; SYM1B; SYNS2
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN407105 GDF5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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