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Human PTP4A2 activation kit by CRISPRa

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SKU
GA105399
PTP4A2 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase 4A2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA324079 Anti-PTP4A2 rabbit polyclonal antibody
100 ul
$305.00
RC209983 PTP4A2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase type IVA, member 2 (PTP4A2), transcript variant 1
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Other products for "PTP4A2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTP4A2
Locus ID 8073
Components

GA105399G1, PTP4A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105399G2, PTP4A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105399G3, PTP4A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001195100, NM_001195101, NM_003479, NM_080391, NM_080392, N21082, NM_001369858, NM_001369860, NM_001369859
UniProt ID Q12974
Synonyms HH7-2; HH13; HU-PP-1; OV-1; PRL-2; PRL2; ptp-IV1a; ptp-IV1b; PTP4A; PTPCAAX2
Summary The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. provided by RefSeq, Aug 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN409983 PTP4A2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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