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Human DAP3 activation kit by CRISPRa

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SKU
GA105326
DAP3 CRISPRa kit - CRISPR gene activation of human death associated protein 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA802927 DAP3 mouse monoclonal antibody, clone OTI1B12 (formerly 1B12) 100 ul
$447.00
RC223182 DAP3 (Myc-DDK-tagged)-Human death associated protein 3 (DAP3), nuclear gene encoding mitochondrial protein, transcript variant 1
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Other products for "DAP3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DAP3
Locus ID 7818
Components

GA105326G1, DAP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105326G2, DAP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105326G3, DAP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001199849, NM_001199850, NM_001199851, NM_004632, NM_033657
UniProt ID P51398
Synonyms bMRP-10; DAP-3; MRP-S29; MRPS29
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. provided by RefSeq, Dec 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN419744 DAP3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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