Human WNT8B activation kit by CRISPRa

SKU GA105155

WNT8B CRISPRa kit - CRISPR gene activation of human Wnt family member 8B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: WNT8B
• Locus ID: 7479
• Components:

  GA105155G1, WNT8B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105155G2, WNT8B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105155G3, WNT8B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003393
• UniProt ID: Q93098
• Synonyms: OTTHUMP00000020285; wingless-type MMTV integration site family, member 8B
• Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008]