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Human WASP (WAS) activation kit by CRISPRa

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SKU
GA105136
WAS CRISPRa kit - CRISPR gene activation of human WASP actin nucleation promoting factor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA326875 WAS Rabbit Polyclonal Antibody
100 ul
$410.00
RC203457 WAS (Myc-DDK-tagged)-Human Wiskott-Aldrich syndrome (eczema-thrombocytopenia) (WAS)
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$467.00

Other products for "WAS"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WAS
Locus ID 7454
Components

GA105136G1, WASP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105136G2, WASP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105136G3, WASP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000377
UniProt ID P42768
Synonyms IMD2; SCNX; THC; THC1; WASP; WASPA
Summary The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN203457 WAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203457BN WAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203457LP WAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203457RB WAS - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403457 WAS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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