Human TYRO3 activation kit by CRISPRa

SKU GA105030

TYRO3 CRISPRa kit - CRISPR gene activation of human TYRO3 protein tyrosine kinase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TYRO3
• Locus ID: 7301
• Components:

  GA105030G1, TYRO3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105030G2, TYRO3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105030G3, TYRO3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006293, NM_001330264
• UniProt ID: Q06418
• Synonyms: BYK; Dtk; Etk-2; Rek; RSE; Sky; Tif
• Summary: The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]