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Human TJP1 activation kit by CRISPRa

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SKU
GA104884
TJP1 CRISPRa kit - CRISPR gene activation of human tight junction protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA341679 Rabbit Polyclonal Anti-TJP1 Antibody
100 ul
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RC222836 TJP1 (Myc-DDK-tagged)-Human tight junction protein 1 (zona occludens 1) (TJP1), transcript variant 1
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Other products for "TJP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TJP1
Locus ID 7082
Components

GA104884G1, TJP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104884G2, TJP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104884G3, TJP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001301025, NM_001301026, NM_003257, NM_175610, NM_001330239, NM_001355012, NM_001355013, NM_001355014, NM_001355015
UniProt ID Q07157
Synonyms ZO-1
Summary This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN216224 TJP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216224BN TJP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216224LP TJP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216224RB TJP1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416224 TJP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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