Human TIA1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | TIA1 |
| Locus ID | 7072 |
| Components |
GA104875G1, TIA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104875G2, TIA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104875G3, TIA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_022037, NM_022173, NM_001351508, NM_001351509, NM_001351510, NM_001351511, NM_001351512, NM_001351513, NM_001351514, NM_001351515, NM_001351516, NM_001351517, NM_001351518, NM_001351519, NM_001351520, NM_001351521, NM_001351522, NM_001351523, NM_001351524, NM_001351525, NR_147216, NR_147217, NR_147218, NR_147219, NR_147220, NR_147221, NR_147222, NR_147223, NR_147224, NR_147225, NR_147226, NR_147227, NR_147228, NR_147229, NR_147230, NR_147231, NR_147232 |
| UniProt ID | P31483 |
| Synonyms | TIA-1; WDM |
| Summary | The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. provided by RefSeq, May 2017 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN415053 | TIA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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