Human TAK1 (MAP3K7) activation kit by CRISPRa

SKU
GA104744
MAP3K7 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase kinase 7
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MAP3K7
Locus ID 6885
Components

GA104744G1, TAK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104744G2, TAK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104744G3, TAK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_003188, NM_145331, NM_145332, NM_145333
UniProt ID O43318
Synonyms MEKK7; TAK1; TGF1a
Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN204454 MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204454BN MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204454LP MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204454RB MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404454 MAP3K7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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