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TAK1 (MAP3K7) Human Gene Knockout Kit (CRISPR)

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SKU
KN204454BN
MAP3K7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "TAK1 or NM_003188"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol TAK1
Locus ID 6885
Components

KN204454G1, TAK1 gRNA vector 1 in pCas-Guide CRISPR vector

KN204454G2, TAK1 gRNA vector 2 in pCas-Guide CRISPR vector

KN204454BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003188, NM_145331, NM_145332, NM_145333
UniProt ID O43318
Synonyms MEKK7; TAK1; TGF1a
Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA104744 MAP3K7 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase kinase 7 1 kit
$1,657.00
KN204454 MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204454LP MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204454RB MAP3K7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404454 MAP3K7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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