Human SPR activation kit by CRISPRa

SKU GA104597

SPR CRISPRa kit - CRISPR gene activation of human sepiapterin reductase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SPR
• Locus ID: 6697
• Components:

  GA104597G1, SPR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104597G2, SPR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104597G3, SPR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003124
• UniProt ID: P35270
• Synonyms: SDR38C1
• Summary: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]