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Human CD43 (SPN) activation kit by CRISPRa

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SKU
GA104593
SPN CRISPRa kit - CRISPR gene activation of human sialophorin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA800785 SPN (CD43) mouse monoclonal antibody, clone OTI6A4 (formerly 6A4) 100 ul
$447.00
RC204195 SPN (Myc-DDK-tagged)-Human sialophorin (SPN), transcript variant 2
10 ug
$457.00

Other products for "SPN"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPN
Locus ID 6693
Components

GA104593G1, CD43 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104593G2, CD43 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104593G3, CD43 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001030288, NM_003123
UniProt ID P16150
Synonyms CD43; GALGP; GPL115; LSN
Summary This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. provided by RefSeq, Sep 2017
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Resources
Other Versions
SKU Description Size Price
KN404195 SPN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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