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Human CXCL11 activation kit by CRISPRa

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SKU
GA104334
CXCL11 CRISPRa kit - CRISPR gene activation of human C-X-C motif chemokine ligand 11
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210320 CXCL11 (Myc-DDK-tagged)-Human chemokine (C-X-C motif) ligand 11 (CXCL11)
10 ug
$289.00

Other products for "CXCL11"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CXCL11
Locus ID 6373
Components

GA104334G1, CXCL11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104334G2, CXCL11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104334G3, CXCL11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001302123, NM_005409
UniProt ID O14625
Synonyms b-R1; H174; I-TAC; IP-9; IP9; SCYB9B; SCYB11
Summary Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2014
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Other Versions
SKU Description Size Price
KN410320 CXCL11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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