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Human PRPH2 activation kit by CRISPRa

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SKU
GA104060
PRPH2 CRISPRa kit - CRISPR gene activation of human peripherin 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210357 PRPH2 (Myc-DDK-tagged)-Human peripherin 2 (retinal degeneration, slow) (PRPH2)
10 ug
$457.00

Other products for "PRPH2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRPH2
Locus ID 5961
Components

GA104060G1, PRPH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104060G2, PRPH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104060G3, PRPH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000322
UniProt ID P23942
Synonyms AOFMD; AVMD; CACD2; DS; MDBS1; PRPH; rd2; RDS; RP7; TSPAN22
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN410357 PRPH2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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