Human RASGRF2 activation kit by CRISPRa

SKU GA104034

RASGRF2 CRISPRa kit - CRISPR gene activation of human Ras protein specific guanine nucleotide releasing factor 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RASGRF2
• Locus ID: 5924
• Components:

  GA104034G1, RASGRF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104034G2, RASGRF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104034G3, RASGRF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006909
• UniProt ID: O14827
• Synonyms: GRF2; RAS-GRF2
• Summary: RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]