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Human CD45 (PTPRC) activation kit by CRISPRa

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SKU
GA103932
PTPRC CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type C
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC216590 PTPRC (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, C (PTPRC), transcript variant 1
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Other products for "PTPRC"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPRC
Locus ID 5788
Components

GA103932G1, CD45 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103932G2, CD45 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103932G3, CD45 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001267798, NM_002838, NM_080921, NM_080922, NM_080923, NR_052021
UniProt ID P08575
Synonyms B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. provided by RefSeq, Jun 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN216590 PTPRC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216590BN PTPRC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216590LP PTPRC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216590RB PTPRC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416590 PTPRC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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