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Human PSMC5 activation kit by CRISPRa

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SKU
GA103873
PSMC5 CRISPRa kit - CRISPR gene activation of human proteasome 26S subunit, ATPase 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA335803 Rabbit Polyclonal Anti-PSMC5 Antibody
100 ul
$525.00
RC201251 PSMC5 (Myc-DDK-tagged)-Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1
10 ug
$457.00

Other products for "PSMC5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PSMC5
Locus ID 5705
Components

GA103873G1, PSMC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103873G2, PSMC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103873G3, PSMC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001199163, NM_002805
UniProt ID P62195
Synonyms p45; p45/SUG; S8; SUG-1; SUG1; TBP10; TRIP1
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN401251 PSMC5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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