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Human Phosphorylase B (PHKB) activation kit by CRISPRa

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SKU
GA103530
PHKB CRISPRa kit - CRISPR gene activation of human phosphorylase kinase regulatory subunit beta
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350281 Rabbit Polyclonal Anti-PHKB Antibody
100 ul
$205.00
RC207611 PHKB (Myc-DDK-tagged)-Human phosphorylase kinase, beta (PHKB), transcript variant 2
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$945.00

Other products for "PHKB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PHKB
Locus ID 5257
Components

GA103530G1, Phosphorylase B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103530G2, Phosphorylase B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103530G3, Phosphorylase B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000293, NM_001031835, NM_001363837
UniProt ID Q93100
Synonyms DKFZp781E15103; FLJ41698
Summary Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.provided by RefSeq, Feb 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN407611 PHKB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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