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Human PGK1 activation kit by CRISPRa

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SKU
GA103515
PGK1 CRISPRa kit - CRISPR gene activation of human phosphoglycerate kinase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA349646 Rabbit Polyclonal Anti-PGK1 Antibody
100 ul
$205.00
RC211172 PGK1 (Myc-DDK-tagged)-Human phosphoglycerate kinase 1 (PGK1)
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Other products for "PGK1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PGK1
Locus ID 5230
Components

GA103515G1, PGK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103515G2, PGK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103515G3, PGK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000291
UniProt ID P00558
Synonyms HEL-S-68p; MIG10; PGKA
Summary The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. provided by RefSeq, Jan 2014
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Other Versions
SKU Description Size Price
KN411172 PGK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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