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Human PFKFB3 activation kit by CRISPRa

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SKU
GA103499
PFKFB3 CRISPRa kit - CRISPR gene activation of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA379831 PFKFB3 Rabbit polyclonal Antibody
100 ul
$410.00
RC206043L1V Lenti ORF particles, PFKFB3 (Myc-DDK tagged) - Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), transcript variant 1, 200ul, >10^7 TU/mL
200 ul
$1,034.00

Other products for "PFKFB3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PFKFB3
Locus ID 5209
Components

GA103499G1, PFKFB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103499G2, PFKFB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103499G3, PFKFB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001145443, NM_001282630, NM_001314063, NM_001323016, NM_001323017, NM_004566, NR_136554, NM_001363545
UniProt ID Q16875
Synonyms iPFK-2; IPFK2; PFK2
Summary The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN206043 PFKFB3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206043BN PFKFB3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206043LP PFKFB3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN206043RB PFKFB3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN406043 PFKFB3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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