PFKFB3 Rabbit Polyclonal Antibody

SKU TA379831

PFKFB3 Rabbit polyclonal Antibody

Product Data

• Application: ELISA, IHC, WB
• Recommended Dilution: WB,1:100 - 1:500; IHC-P,1:50 - 1:200; ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivity: Human, Mouse, Rat
• Modification: Unmodified
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Buffer: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 60kDa
• Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
• Database Link:
  Q16875
• Background: The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatas; FLJ37326; iPFK-2; IPFK2; PFK2

Reference Data