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Human PDE3A activation kit by CRISPRa

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SKU
GA103436
PDE3A CRISPRa kit - CRISPR gene activation of human phosphodiesterase 3A
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC222006 PDE3A (Myc-DDK-tagged)-Human phosphodiesterase 3A, cGMP-inhibited (PDE3A)
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Other products for "PDE3A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE3A
Locus ID 5139
Components

GA103436G1, PDE3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103436G2, PDE3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103436G3, PDE3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000921, NM_001244683
UniProt ID Q14432
Synonyms CGI-PDE; CGI-PDE-A; CGI-PDE A
Summary This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Sep 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN422006 PDE3A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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