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Human NOTCH4 activation kit by CRISPRa

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SKU
GA103242
NOTCH4 CRISPRa kit - CRISPR gene activation of human notch receptor 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA355566 NOTCH4 Antibody - middle region
100 ul
$585.00
RC221762 NOTCH4 (Myc-DDK-tagged)-Human notch 4 (NOTCH4)
10 ug
$2,479.00

Other products for "NOTCH4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NOTCH4
Locus ID 4855
Components

GA103242G1, NOTCH4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103242G2, NOTCH4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103242G3, NOTCH4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004557, NR_134949, NR_134950
UniProt ID Q99466
Synonyms INT3
Summary This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN221762 NOTCH4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221762BN NOTCH4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221762LP NOTCH4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221762RB NOTCH4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN421762 NOTCH4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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