OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human NOTCH2 activation kit by CRISPRa

Be the first to review this product
SKU
GA103240
NOTCH2 CRISPRa kit - CRISPR gene activation of human notch receptor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215107 NOTCH2 (Myc-DDK-tagged)-Human notch 2 (NOTCH2), transcript variant 1
10 ug
$3,058.00

Other products for "NOTCH2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NOTCH2
Locus ID 4853
Components

GA103240G1, NOTCH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103240G2, NOTCH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103240G3, NOTCH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001200001, NM_024408
UniProt ID Q04721
Synonyms AGS2; HJCYS; hN2
Summary This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2011
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN215107 NOTCH2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215107BN NOTCH2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215107LP NOTCH2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215107RB NOTCH2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415107 NOTCH2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products