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Human NEDD8 activation kit by CRISPRa

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SKU
GA103162
NEDD8 CRISPRa kit - CRISPR gene activation of human NEDD8 ubiquitin like modifier
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "NEDD8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NEDD8
Locus ID 4738
Components

GA103162G1, NEDD8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103162G2, NEDD8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103162G3, NEDD8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006156
UniProt ID Q15843
Synonyms NEDD-8
Summary Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN410479 NEDD8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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