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Human MMP12 activation kit by CRISPRa

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SKU
GA102941
MMP12 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 12
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC223246 MMP12 (Myc-DDK-tagged)-Human matrix metallopeptidase 12 (macrophage elastase) (MMP12)
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Other products for "MMP12"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MMP12
Locus ID 4321
Components

GA102941G1, MMP12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102941G2, MMP12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102941G3, MMP12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002426
UniProt ID P39900
Synonyms HME; ME; MME; MMP-12
Summary This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. provided by RefSeq, Jan 2016
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Other Versions
SKU Description Size Price
KN423246 MMP12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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