MMP12 Rabbit Polyclonal Antibody

SKU TA349399

Rabbit Polyclonal Anti-MMP12 Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 200-1000; WB positive control: 293T cell lysate; IHC: 50-200; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human MMP12
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: matrix metallopeptidase 12
• Database Link:
  NP_002417
  P39900
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin.
• Synonyms: HME; ME; MME; MMP-12

Reference Data

• Protein Families: Druggable Genome, Protease