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Human MGMT activation kit by CRISPRa

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SKU
GA102900
MGMT CRISPRa kit - CRISPR gene activation of human O-6-methylguanine-DNA methyltransferase
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC229131 MGMT (Myc-DDK-tagged)-Human O-6-methylguanine-DNA methyltransferase (MGMT)
10 ug
$450.00

Other products for "MGMT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MGMT
Locus ID 4255
Components

GA102900G1, MGMT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102900G2, MGMT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102900G3, MGMT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_002412
UniProt ID P16455
Synonyms methylguanine-DNA methyltransferase; O-6-methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; OTTHUMP00000020741
Summary Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN201612 MGMT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201612BN MGMT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201612LP MGMT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201612RB MGMT - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401612 MGMT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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