Human LRP3 activation kit by CRISPRa

SKU GA102734

LRP3 CRISPRa kit - CRISPR gene activation of human LDL receptor related protein 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LRP3
• Locus ID: 4037
• Components:

  GA102734G1, LRP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102734G2, LRP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102734G3, LRP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002333
• UniProt ID: O75074
• Synonyms: low density lipoprotein receptor-related protein 3
• Summary: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.[UniProtKB/Swiss-Prot Function]