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LRP3 Rabbit Polyclonal Antibody

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SKU
TA323023
Anti-LRP3 Rabbit Polyclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $305.00
In Stock*
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Frequently Bought Together (2)

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View other "LRP3 or NM_002333" antibodies

Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 100-300
Positive control: Human brain
Predicted cell location: Cytoplasm, Cell membrane
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 686-699 amino acids of Human low density lipoprotein receptor-related protein 3
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name LDL receptor related protein 3
Database Link
Background Low density lipoprotein receptor-related protein 3?(LRP-3) is a?protein?that in humans is encoded by theLRP3?gene. Probable receptor; which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear; since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
Synonyms low density lipoprotein receptor-related protein 3
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
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Documents
Resources

file-alt Citations

Cholesterol-induced LRP3 downregulation promotes cartilage degeneration in osteoarthritis by targeting Syndecan-4
Cao, Shi, Zhang et al
Nat Commun (2022) 13 (1), 7139 DOI: 10.1038/s41467-022-34830-4
Cited by 75
AI Summary: OriGene's LRP3 antibody (TA323023) was used to detect LRP3 protein expression in rat and mouse cartilage tissue, contributing to the study’s analysis of LRP3 involvement in osteoarthritis progression.
Snippet: … Next, the sections were incubated with specific primary antibodies against COL2A1 (ab34712;Abcam;1:100), LRP3 (human: ab115197;1:50) (rat/mouse: TA323023;Origene, USA;1:50), and SDC4 (ab74139;1:50), and ARGSVIL (ab3773;1:50) overnight at 4 °C. …
FigureFigureFigure
IHC
Cholesterol-induced LRP3 downregulation promotes cartilage degeneration in osteoarthritis by targeting SDC4
Cao, Shi, Xin et al
Research Square (2021)
Snippet: antibodies against COL2A1 (ab34712;Abcam;1:100), LRP3 (human: ab115197;1:50) (rat/mouse: TA323023;Origene, USA;1:50), and SDC4 (ab74139;1:50), and VAGSVIL (ab3773;1:50) overnight at 4 °C
Showing 1-2 of 2 papers.
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