Human Integrin beta 1 (ITGB1) activation kit by CRISPRa

SKU GA102477

ITGB1 CRISPRa kit - CRISPR gene activation of human integrin subunit beta 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ITGB1
• Locus ID: 3688
• Components:

  GA102477G1, Integrin beta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102477G2, Integrin beta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102477G3, Integrin beta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002211, NM_033666, NM_033667, NM_033668, NM_033669, NM_133376
• UniProt ID: P05556
• Synonyms: CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB
• Summary: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]