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Human IL6R activation kit by CRISPRa

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SKU
GA102387
IL6R CRISPRa kit - CRISPR gene activation of human interleukin 6 receptor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "IL6R"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL6R
Locus ID 3570
Components

GA102387G1, IL6R gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102387G2, IL6R gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102387G3, IL6R gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000565, NM_001206866, NM_181359
UniProt ID P08887
Synonyms CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ
Summary This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. provided by RefSeq, Aug 2020
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Documents
Resources
Other Versions
SKU Description Size Price
KN419601 IL6R - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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