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Human IL6 activation kit by CRISPRa

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SKU
GA102386
IL6 CRISPRa kit - CRISPR gene activation of human interleukin 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500067 IL6 mouse monoclonal antibody, clone OTI3G9 (formerly 3G9) 100 ul
$447.00
RC202078 IL6 (Myc-DDK-tagged)-Human interleukin 6 (interferon, beta 2) (IL6)
10 ug
$450.00

Other products for "IL6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IL6
Locus ID 3569
Components

GA102386G1, IL6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102386G2, IL6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102386G3, IL6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000600, NM_001318095
UniProt ID P05231
Synonyms BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Summary This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). provided by RefSeq, Aug 2020
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Documents
Resources
Other Versions
SKU Description Size Price
KN202078 IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202078BN IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202078LP IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202078RB IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402078 IL6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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