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IL6 Human Gene Knockout Kit (CRISPR)

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SKU
KN202078RB
IL6 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "IL6 or BC015511"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol IL6
Locus ID 3569
Components

KN202078G1, IL6 gRNA vector 1 in pCas-Guide CRISPR vector

KN202078G2, IL6 gRNA vector 2 in pCas-Guide CRISPR vector

KN202078RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000600, NM_001318095
UniProt ID P05231
Synonyms BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Summary This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). provided by RefSeq, Aug 2020
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Other Versions
SKU Description Size Price
GA102386 IL6 CRISPRa kit - CRISPR gene activation of human interleukin 6 1 kit
$1,657.00
KN202078 IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202078BN IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202078LP IL6 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402078 IL6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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