Human IDI1 activation kit by CRISPRa

SKU GA102315

IDI1 CRISPRa kit - CRISPR gene activation of human isopentenyl-diphosphate delta isomerase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: IDI1
• Locus ID: 3422
• Components:

  GA102315G1, IDI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102315G2, IDI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102315G3, IDI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001317955, NM_001317956, NM_001317957, NM_004508, NR_134300, NR_134301
• UniProt ID: Q13907
• Synonyms: IPP1; IPPI1
• Summary: IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008]