IDI1 Rabbit Polyclonal Antibody

SKU TA308665

Rabbit polyclonal antibody to IDI1 (isopentenyl-diphosphate delta isomerase 1)

Product Data

• Application: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivity: Bovine, Human (Predicted: Mouse, Rat, X. tropicalis), Xenopus, Zebrafish
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 173 of IDI1 (Uniprot ID#Q13907)
• Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 32 kDa
• Gene Name: isopentenyl-diphosphate delta isomerase 1
• Database Link:
  NP_004499
  Q13907
• Background: IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq]
• Synonyms: IPP1; IPPI1
• Note: Seq homology of immunogen across species: Mouse (87%), Rat (85%), Xenopus laevis (80%), Zebrafish (81%), Bovine (89%), Xenopus tropicalis (81%)

Reference Data

• Protein Pathways: Metabolic pathways, Terpenoid backbone biosynthesis