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Human HUS1 activation kit by CRISPRa

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SKU
GA102292
HUS1 CRISPRa kit - CRISPR gene activation of human HUS1 checkpoint clamp component
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308100 Rabbit polyclonal antibody to HUS1 (HUS1 checkpoint homolog (S. pombe))
100 ul
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RC202727 HUS1 (Myc-DDK-tagged)-Human HUS1 checkpoint homolog (S. pombe) (HUS1), transcript variant 1
10 ug
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Other products for "HUS1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HUS1
Locus ID 3364
Components

GA102292G1, HUS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102292G2, HUS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102292G3, HUS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004507, NR_037917, NM_001363683
UniProt ID O60921
Synonyms hHUS1
Summary The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2011
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Other Versions
SKU Description Size Price
KN402727 HUS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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