Human HIP1 activation kit by CRISPRa

SKU GA102108

HIP1 CRISPRa kit - CRISPR gene activation of human huntingtin interacting protein 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: HIP1
• Locus ID: 3092
• Components:

  GA102108G1, HIP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102108G2, HIP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102108G3, HIP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001243198, NM_005338
• UniProt ID: O00291
• Synonyms: HIP-I; ILWEQ; SHON; SHONbeta; SHONgamma
• Summary: The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain; this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]