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Human MSH6 activation kit by CRISPRa

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SKU
GA102001
MSH6 CRISPRa kit - CRISPR gene activation of human mutS homolog 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC202469 MSH6 (Myc-DDK-tagged)-Human mutS homolog 6 (E. coli) (MSH6)
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Other products for "MSH6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MSH6
Locus ID 2956
Components

GA102001G1, MSH6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102001G2, MSH6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102001G3, MSH6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000179, NM_001281492, NM_001281493, NM_001281494
UniProt ID P52701
Synonyms GTBP; GTMBP; HNPCC5; HSAP; p160
Summary This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN402469 MSH6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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