Human Glutaredoxin 1 (GLRX) activation kit by CRISPRa

SKU
GA101832
GLRX CRISPRa kit - CRISPR gene activation of human glutaredoxin
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GLRX
Locus ID 2745
Components

GA101832G1, Glutaredoxin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101832G2, Glutaredoxin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101832G3, Glutaredoxin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001118890, NM_001243658, NM_001243659, NM_002064
UniProt ID P35754
Synonyms GRX; GRX1
Summary This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. provided by RefSeq, Aug 2011
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Other Versions
SKU Description Size Price
KN419385 GLRX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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