Human FNTA activation kit by CRISPRa

SKU GA101642

FNTA CRISPRa kit - CRISPR gene activation of human farnesyltransferase, CAAX box, alpha

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FNTA
• Locus ID: 2339
• Components:

  GA101642G1, FNTA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101642G2, FNTA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101642G3, FNTA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001018676, NM_001018677, NM_002027, NR_033698
• UniProt ID: P49354
• Synonyms: FPTA; MGC99680; PGGT1A; PTAR2
• Summary: Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]