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Human FOXM1 activation kit by CRISPRa

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SKU
GA101615
FOXM1 CRISPRa kit - CRISPR gene activation of human forkhead box M1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA330367 Rabbit Polyclonal Anti-FOXM1 Antibody
100 ul
$585.00
RC202246 FOXM1 (Myc-DDK-tagged)-Human forkhead box M1 (FOXM1), transcript variant 2
10 ug
$699.00

Other products for "FOXM1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FOXM1
Locus ID 2305
Components

GA101615G1, FOXM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101615G2, FOXM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101615G3, FOXM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001243088, NM_001243089, NM_021953, NM_202002, NM_202003
UniProt ID Q08050
Synonyms FKHL16; FOXM1B; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TGT3; TRIDENT
Summary The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN402246 FOXM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor)
Ben Djoudi Ouadda, Gauthier, Susan-Resiga et al
Arterioscler. Thromb. Vasc. Biol. (2019) 39 (10), 1996-2013 DOI: 10.1161/ATVBAHA.119.313247
AI Summary: OriGene’s genome-wide gene knockout kit (pCas-Guide vector and pUC-turboGFP-puro donor vector) was used to generate targeted gene knockouts in cells, enabling the study of PCSK9 phosphorylation and its effects on LDLR degradation.
Snippet: Cells were co-transfected with 8 µg of pCas-Guide vector and 8 µg of pUC-turboGFP-puro donor vector (Origene genome-wide gene knockout kit) using Lipofectamine 3000 (Thermo Fisher Scientific) according to the manufacturer protocol
Immobilization of Recombinant Human Catalase on Gold and Silver Nanoparticles
Pudlarz, Czechowska, Ranoszek-Soliwoda et al
Appl Biochem Biotechnol (2018) 185 (3), 717-735 DOI: 10.1007/s12010-017-2682-2
Cited by 33
AI Summary: In this study, the human catalase cDNA and the pEX-C-His vector from OriGene were used to produce recombinant catalase, which was subsequently immobilized on gold and silver nanoparticles to assess enzyme stability and activity.
Decreased Eph receptor‑A1 expression is related to grade in ovarian serous carcinoma
Jin, Zou, Wan et al
Mol Med Rep (2018)
AI Summary: OriGene’s EphA1‑pCMV6‑GFP eukaryotic expression vector kit was used to overexpress EphA1 in ovarian cancer cell lines, enabling the study of its effects on cell proliferation and its association with tumor grade in ovarian serous carcinoma.
Snippet: Data were acquired with approval from the Ethics Committee of the Affiliated Hospital of Nantong University. EphA1 plasmid transfection. The plasmid EphA1‑pCMV6‑ GFP eukaryotic expression vector kit was purchased from OriGene Technologies, Inc (Rockville, MD
Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
Murphy, Weyhenmeyer, Noonan et al
Apoptosis (2013)
Cited by 48
AI Summary: OriGene’s human Mcl-1 and Noxa knockdown 29mer shRNA constructs in retroviral GFP vectors were used to silence these genes in glioblastoma cells, enabling the study to demonstrate how targeting Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis.
Snippet: A172, U87 and MZ-294 cells were transfected with human Mcl-1 knockdown 29mer shRNA construct in a retroviral GFP vector (Origene) and MZ-294 cells were transfected with human Noxa knockdown 29mer shRNA construct in a retroviral GFP vector (Origene) using ... Cite SaveSaving
MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation
Bian, Traurig, Hanson et al
Hum. Mol. Genet. (2013)
Cited by 31
AI Summary: In this study, OriGene’s TrueClone MAP2K3 cDNA clone was used to investigate the role of MAP2K3 in hypothalamic inflammation and adipogenesis, contributing to the functional analysis of this gene’s association with body mass index.
Snippet: We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Find out more. Skip Navigation.
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